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type: stuff

Nilotinib is an inhibitor of the BCR-ABL kinase. Nilotinib binds to and stabilizes the inactive conformation of the kinase domain of ABL protein. In vitro, nilotinib inhibited BCR-ABL mediated proliferation of murine leukemic cell lines and human more

Kimotar (Erlotinib)

type: stuff

Kimotar® inhibits the intracellular phosphorylation of tyrosine kinase associated with the epidermal growth factor receptor. Kimotar® expressed on the cell surface of healthy cells and cancer cells, and prevents autophosphorylation of more